5-MTHF, provided as Quatrefolic, is the most biologically active form of the water-soluble B vitamin, folic acid. It is the preferred form of folate supplementation due to an array of conditions that can limit the conversion or absorption of folic acid. Data indicate that supplementing with 5-MTHF increases plasma folate more effectively than folic acid.*

*Follow recommended dosing or use as directed by your healthcare practitioner. Individuals taking medication should discuss potential interactions with their healthcare practitioner prior to use. These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.